Effect of ghrelin on activities of some lysosomal hydrolases in rabbits.

نویسندگان

  • Bozena Witek
  • Ewa Ochwanowska
  • Jan Rafay
  • Adam Kolataj
  • Peter Chrenek
  • Karin Suvegova
  • Rastislav Jurcik
  • Alexander Sirotkin
  • Krzysztof Darlak
چکیده

OBJECTIVES Observing the changes of activity of some lysosomal enzymes in blood serum of female rabbits subjected to injection of 10 microg of ghrelin/kg of body weight. METHODS In the blood serum the activity of cathepsins D and L, alanine aminopeptidase, acid phosphatase, lysosomal lipase and lysosomal esterase was determined. RESULTS As a result of ghrelin injection the activity of all the enzymes examined in blood serum increased markedly. CONCLUSION Changes of lysosomal enzymes activities in the blood serum caused by the effects of ghrelin should be regarded as the response of the lysosomal system.

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عنوان ژورنال:
  • Neuro endocrinology letters

دوره 26 4  شماره 

صفحات  -

تاریخ انتشار 2005